Tuesday, December 24, 2019

The War Of 1812 Was A Two Year Long War - 1430 Words

The war of 1812 was a two-year-long war fought between the United States and Great Britain. The war was triggered between the two nations over the issue of impressment of American soldiers, and although Britain promised to stop, they continued to do so anyway, hence taunting the United States into entering the war. Now although the Americans â€Å"lost† the war, they did win something as a result of the two-year battle and that was nationalism which later manifested itself in the country’s judicial decisions, culture, politics, and foreign policy. After the war of 1812, Americans sought ways to better their country politically. Before the war, American life was rural and the development of the country side was slow. However, after the war and†¦show more content†¦With more wealth, more ideas were beginning to surface on how to better the American lifestyle amongst the states; one of those ideas was â€Å"The American System† brought up by Henry Clay. The goals of this system was to increase the country’s wealth with an effective banking system, creating a set of roads and canals throughout the country to unite the states and spread information further, and do all that in correlation to another protective tariff placed on oversea trading. So as you can see because nationalism manifested itself in American politics to unite the country even more, different methods were proposed and carried out to better American lifestyle. Even when congress deemed some methods unconstitutional, the states sought individu al ways in which they could improve the U.S like New York’s construction of the Erie Canal. Nevertheless, the country began to undergo positive changes as a result of the political nationalism rising in the country. Culture is a part of everyday life and in the years to come after the war of 1812, nationalism would eventually manifest itself in American culture as well. American culture was usually demonstrated or portrayed through paintings, books, songs, and more. Now in order to grasp the concept of cultural nationalism, it’s important to realize that Britain and the United States have fought once before where the U.S. Came out the victor. In the war of 1812, they fought against Britain and although

Monday, December 16, 2019

Clinical Trial and Nucleon Assignment Notes Free Essays

Nucleon Assignment Notes Porter’s 5 Forces Industry Analysis †¢Competition: Intense †¢Buyer Power: Moderate to High oBig pharma companies likely have a lot of power, although as a small firm, your power increases once you clear phases of drug trials. †¢Supplier Power: Unsure, Moderate? oThe case makes it sound like there’s not many manufacturers out there for contracting purposes. Not sure what power suppliers of raw materials have. We will write a custom essay sample on Clinical Trial and Nucleon Assignment Notes or any similar topic only for you Order Now †¢Threat of Substitutes: Moderate to High oLots of firms racing to create the next blockbuster drug or treatment for big money illnesses. However, most drugs fail, so the likelihood of a substitute is probably only moderate. †¢Threat of New Entrants: Moderate oRelatively easy to start a new small drug research firm. Just need some smart scientists. Funding is currently difficult to come by, however. Nucleon †¢Competition: Moderate to Low oThe case mentioned they were in a pretty niche area of biotech. †¢Buyer Power: Moderate to High oBig pharma companies likely have a lot of power. But if Nucleon clears phase II their power increases substantially. †¢Supplier Power: Unsure, Moderate? The case makes it sound like there’s not many manufacturers out there for contracting purposes. Not sure what power suppliers of raw materials have. †¢Threat of Substitutes: Moderate to Low oI don’t think there’s much out there in the way of burn treatments (need to check on that). †¢Threat of New Entrants: Moderate to Low oThe drug research process is slow, so any new entrant in this spec ific area is going to be significantly behind with little to no way to catch up. Resource Based View VRIO Value:There’s definitely value in a successful drug for burn treatment; it also presents itself as a possible cure for other ailments as well (i. . kidney failure) Rarity:Not many alternatives for burn victim treatment (assumption based on the case’s voice); large molecule research is still new and rare, tough to get into. Imitability: Not very imitable, especially if Nucleon can gain strong patent protection. Also, the slow development time means that even if another firm could mimic a similar drug, it would take time. Organization:Nucleon is currently not organized to begin trials and manufacturing of this drug. They also don’t have a significant amount of financial backing at this point. Transaction Based Economics Hold-ups †¢Contract manufacturer could hold up Nucleon for more money if drug passes phases and becomes more likely to be successful. †¢Contract manufacturer could increase manufacturing costs, slow production, or create problems in quality in order to hold up Nucleon. Options Going Forward Option 1: Build Pilot Plant Pros †¢Nucleon keeps tighter control of IP †¢Can retain ownership of product rights through phase I and II †¢More flexibility †¢Can begin to develop staff for in-house manufacturing, making scaling later easier Cons Expensive (likely need more financial backing/don’t have enough as is) †¢Risky oDrug could fail in clinical trials (which statistically is likely) oProcess uncertainty; bacterial vs. mammalian cells †¢Distracts Nucleon’s financial and human capital away from their core, the drug RD Option 2: Contract Manufacturing Pros †¢No major upfront capital investment †¢Access to experienced manufacturing facilities and staff immediately †¢Retain ownership of product rights through phase I and II Cons †¢Still not cheap; doesn’t save Nucleon much money over Option 1 †¢Risk of IP issues Contract specifics are very difficult to hash out due to the nature of biotech †¢No faster than building their own plant due to slow process of negotiating, knowledge transfer, then scale-up Option 3: Licensing Pros †¢No capital investment †¢Little to no risk †¢Simple; allows Nucleon to focus on the RD †¢Immediate cash flow †¢Keep rights for CRP-1 for other uses (other than for burn treatment) Cons †¢Much less share in the profits if drug is successful (mortgage the company’s success) †¢Would likely lower employee morale, which could in turn decrease likelihood of success of drug †¢Risk of IP issues How to cite Clinical Trial and Nucleon Assignment Notes, Papers Clinical Trial and Nucleon Assignment Notes Free Essays Nucleon Assignment Notes Porter’s 5 Forces Industry Analysis †¢Competition: Intense †¢Buyer Power: Moderate to High oBig pharma companies likely have a lot of power, although as a small firm, your power increases once you clear phases of drug trials. †¢Supplier Power: Unsure, Moderate? oThe case makes it sound like there’s not many manufacturers out there for contracting purposes. Not sure what power suppliers of raw materials have. We will write a custom essay sample on Clinical Trial and Nucleon Assignment Notes or any similar topic only for you Order Now †¢Threat of Substitutes: Moderate to High oLots of firms racing to create the next blockbuster drug or treatment for big money illnesses. However, most drugs fail, so the likelihood of a substitute is probably only moderate. †¢Threat of New Entrants: Moderate oRelatively easy to start a new small drug research firm. Just need some smart scientists. Funding is currently difficult to come by, however. Nucleon †¢Competition: Moderate to Low oThe case mentioned they were in a pretty niche area of biotech. †¢Buyer Power: Moderate to High oBig pharma companies likely have a lot of power. But if Nucleon clears phase II their power increases substantially. †¢Supplier Power: Unsure, Moderate? The case makes it sound like there’s not many manufacturers out there for contracting purposes. Not sure what power suppliers of raw materials have. †¢Threat of Substitutes: Moderate to Low oI don’t think there’s much out there in the way of burn treatments (need to check on that). †¢Threat of New Entrants: Moderate to Low oThe drug research process is slow, so any new entrant in this spec ific area is going to be significantly behind with little to no way to catch up. Resource Based View VRIO Value:There’s definitely value in a successful drug for burn treatment; it also presents itself as a possible cure for other ailments as well (i. . kidney failure) Rarity:Not many alternatives for burn victim treatment (assumption based on the case’s voice); large molecule research is still new and rare, tough to get into. Imitability: Not very imitable, especially if Nucleon can gain strong patent protection. Also, the slow development time means that even if another firm could mimic a similar drug, it would take time. Organization:Nucleon is currently not organized to begin trials and manufacturing of this drug. They also don’t have a significant amount of financial backing at this point. Transaction Based Economics Hold-ups †¢Contract manufacturer could hold up Nucleon for more money if drug passes phases and becomes more likely to be successful. †¢Contract manufacturer could increase manufacturing costs, slow production, or create problems in quality in order to hold up Nucleon. Options Going Forward Option 1: Build Pilot Plant Pros †¢Nucleon keeps tighter control of IP †¢Can retain ownership of product rights through phase I and II †¢More flexibility †¢Can begin to develop staff for in-house manufacturing, making scaling later easier Cons Expensive (likely need more financial backing/don’t have enough as is) †¢Risky oDrug could fail in clinical trials (which statistically is likely) oProcess uncertainty; bacterial vs. mammalian cells †¢Distracts Nucleon’s financial and human capital away from their core, the drug RD Option 2: Contract Manufacturing Pros †¢No major upfront capital investment †¢Access to experienced manufacturing facilities and staff immediately †¢Retain ownership of product rights through phase I and II Cons †¢Still not cheap; doesn’t save Nucleon much money over Option 1 †¢Risk of IP issues Contract specifics are very difficult to hash out due to the nature of biotech †¢No faster than building their own plant due to slow process of negotiating, knowledge transfer, then scale-up Option 3: Licensing Pros †¢No capital investment †¢Little to no risk †¢Simple; allows Nucleon to focus on the RD †¢Immediate cash flow †¢Keep rights for CRP-1 for other uses (other than for burn treatment) Cons †¢Much less share in the profits if drug is successful (mortgage the company’s success) †¢Would likely lower employee morale, which could in turn decrease likelihood of success of drug †¢Risk of IP issues How to cite Clinical Trial and Nucleon Assignment Notes, Essay examples

Sunday, December 8, 2019

Essay The Glass Castle by Jeannette Walls Essay Example For Students

Essay The Glass Castle by Jeannette Walls Essay In this both heart wrenching and slightly humorous memoir, journalist Jeannette Walls tells the bittersweet story of her rather dysfunctional and poverty stricken upbringing. Walls grows up in a family trailed by the ubiquitous presence of hunger and broken homes. Throughout the memoir she recounts memories of moving from one dilapidated neighborhood to another with her three other siblings, insanely free sprinted mother, and incredibly intelligent yet alcoholic father. The author focuses on her unconventional childhood with parents who were too lazy and self-absorbed to obtain decent jobs. Although Wallss childhood gushes with heartbreaking tales of searching through dumpsters for food, she remains as unbitter as possible and instead views her youth in an almost comical light. While most in similar situations observe experiences like these through unforgiving eyes, Walls views her unfortunate experiences through the transparent walls of the glass castle and recalls how she develops the strength and determination to succeed. Although her parents put her through very difficult experiences, she manages to optimistically accept her past and create a much better future for herself. Walls consumes the memoir with depictions of her parents eccentric parenting styles. Although not a drunk like her father she describes her mother as possessing the mentality of a four year old while at the same time being incredibly advanced intellectually. Despite her intelligence, her mother sits around and watches Jeannettes father squander their money on beer and cigarettes while she tries to develop her hidden artistic talents. Even with a teaching degree she refuses to get a job until begged to do so by her starving children. . . so she resolves to overcome her troubled upbringing and turn her life into a success. Although The Glass Castle proves quite an infuriating read, the authors optimism and naivety make the memoir rather refreshing. Walls faces so many unfortunate circumstances and yet still somehow maintains a positive outlook on life. Many who go through similar situations use their less than underprivileged upbringings as excuses for why they remain unable to acquire adequate jobs or prosperous lives, but Walls avoids this completely. Even though her childhood proves rather rough, she realizes this does not prevent her from obtaining her goals. While her life story serves as no fairy tale, she manages to find her happily-ever after through unrelenting faith and determination. Works Cited Walls, Jeannette. The Glass Castle: a Memoir. New York: Scribner, 2006. Print.

Sunday, December 1, 2019

Psychology and Old School Students free essay sample

Psychology of Sport and Exercise †¢ What levels of psychological arousal are most effective for players in team sports? †¢ What methods are available to combat crippling anxiety in competitive sport? †¢ Why exercise hurts: an exploration of the processes and functions of fatigue and pain †¢ How effective can exercise be in combating clinical depression? †¢ How does participation in team sports influence the development of social skills in 12-16 year old school students? * †¢ To what extent does personality affect an elite sportsman’s performance? Psychology and Education †¢ How far is intelligence determined by heredity or how far is it malleable? †¢ What are the pros and cons of ‘hothousing ‘ of young children, as a way to develop precocious talent? †¢ What is the relationship between precocious talent and adult achievement? ( e.g. in Music) †¢ How far can children be taught to excel in the visual Arts? * †¢ Do children who have attended some form of pre-schooling when under the age of 5 yrs have an educational advantage when they start school? †¢ Is the UK government new national curriculum for the under-5’s ‘a threat to all toddlers?’ What is the right age to start (formal) school ? †¢ Which method of teaching reading works best? †¢ Why is dyslexia almost unknown in Italy? †¢ What is the source of the advantage that Chinese children appear to have in Mathematics? * †¢ Is it true that the stages of cognitive development are universal in all cultures? †¢ ‘Spare the rod and spoil the child’. We will write a custom essay sample on Psychology and Old School Students or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page What effects do different disciplinary styles and policies in schools have on the behaviour and development of children? †¢ To what extent does violence in the televised media have the potential to increase the level of aggression within children? †¢ A cross-cultural comparison ( e.g. China/UK ) of the effects of schooling on motivation to learn and educational achievement †¢ A study of the effectiveness of an unusual form of schoong ( e.g. ‘Montessori’ nurseries; Rudolph Steiner schools , ‘Summerhill’. ) †¢ Should boys and girls be educated differently? †¢ What are the causes of gender and subcultural differences in educational achievement in the UK (or elsewhere) and what can or should be done? †¢ How do ‘smart drugs’ affect the brain? What are the ethical issues in the increasing use of ‘cognitive enhancers’ to boost academic performance? Dysfunctional behaviour and effectiveness of treatments and therapies †¢ Where children have been taken into care because of family problems, is it always better in principle to aim to return children to the biological mother? †¢ How important is fathering to children? †¢ Are single-parent families inevitably dysfunctional? †¢ Is depression an illness or a dysfunctional way of thinking? †¢ What are the benefits and risks of SSRI drugs? †¢ Is autism ‘an extreme form of the male brain’? – How far is it true that autism has a biological basis? †¢ How well does the lack of a ‘theory of mind’ account for the characteristic problems of individuals with autistic spectrum disorder (ASD)? †¢ A comparison of different therapeutic interventions in ASD †¢ ‘Oppositional Defiant Disorder’ – a label for children adults can’t control? -Exploration of the arguments and ethical issues around prescribing drugs to children with ADHD and related problems †¢ How do individuals respond to traumatic life experiences? Is it necessary to face past horrors or is it better to deny and suppress in terms of leading a reasonably happy or successful future life? ( NB exemplars need to be restricted to a specific context ) Social and Organizational Psychology and applications †¢ How far can psychology help us overcome prejudices? †¢ Do we all have the potential within us to do evil? †¢ How far can the committing of war atrocities be explained by Milgram’s obedience account? †¢ Can psychology help us to understand how to resolve conflict ( exemplars could be from industrial relations or conflicts between nations ) and negotiate peace ? †¢ What is the best way to be happy at work? Is happiness compatible with productivity? Is there any evidence that companies which treat their workers well are more commercially successful? †¢ What functions does work fulfil for the individual? What are the psychological consequences of current increases in job-insecurity and unemployment arising from the ‘credit-crunch’ ? †¢ How do the main sources of stress or job satisfaction differ between employees in two different employment sectors ( e.g. finance vs teaching ) ? †¢ Are there any common characteristics of ‘good leaders’ or do leaders n eed to exercise different personal qualities or styles of behaviour in different spheres? ( e.g. factory manager, vs army commander ) †¢ Are leaders born or made? †¢ Are leaders really necessary? Criminal Psychology †¢ Pathways to crime: an analysis of the interaction of biological factors and early life experience in ‘turning to crime’ †¢ Can prison work? : an evaluation of the effectiveness of the UK ‘thinking skills programme ‘ †¢ Can empathy be taught? : an evaluation of the ‘Restorative Justice’ initiative in the UK †¢ Nurseries or prisons? : An cost-benefit analysis of the effectiveness of an early intervention programme ( e.g. UK ‘Sure-Start ‘ or ‘YIP’s) †¢ How far can eye (or ear) witness testimony be trusted and what are the implications for the conduct of court proceedings? †¢ Can children be trustworthy witnesses? †¢ To what extent is it possible to make a correct profile of a criminal? †¢ How far can psychological theories and research be applied to help juries make fair decisions? †¢ Creating safe communities: an analysis of the psychology of ‘environmental crime prevention’. †¢ What advice can psychologists give to the police force on how to treat ethnic minorities fairly and avoid ‘institutional racism’? Cognitive and Neuro-Psychology †¢ How can stroke victims be helped to recover their cognitive functions or compensate for missing functions ? ( e.g memory loss) †¢ How far does  current research using fMRI and PET scanning techniques support a modular theory of the organisation of the brain? (This essay might need to be limited in scope by drawing exemplars from one cognitive function, e.g. memory OR language †¢ Is the brain organised differently in bilingual people? †¢How far can the brain recover and reorganise itself after stroke or brain-damage in early life? †¢ Is the capacity for language really unique to humans? †¢ Is it true that dolphins are as intelligent as humans? How could this be tested? †¢ How much can we learn about brain organisation from clinical case –studies ? ( again , might need to restrict exemplars to one cognitive domain) Comments on Aggression mirror neurons – to what extent can parents prevent aggressive behavior in children. No nature v. nurture! Nature v. nurture is overly reductionist and usually do not earn high marks. More topics suggested in the past: What do we know about the relationship between stress and physiological illness and can we use that knowledge to cope with stress? To what extent does psychology provide valid explanations for altruistic behaviour? What effect do autistic siblings have on their non-autistic siblings * Is it possible to determine what causes autism? Which interventions are most efficient in helping autistic children towards a better daily functioning? The difficulties of finding specific genetic factors that can predict a risk for Autism A comparison of the effectiveness of individualized counseling and family counseling in the treatment of anorexia What are the effects of the disruption of the circadian cycle by jetlag and how can the effects be avoided? The extent to which biological (or socio-cultural) factors explain the origin of homosexuality. To what extent do parents discipline style influence the temperament of the children? Montessori schools: based on a humanistic approach to education are they also in line with cognitive theory? To what extent has Criminal Profiling improved investigation methods in cases of homicide? To what extent are the causes of anorexia the result of cultural factors? To what extent is Schizophrenia no longer a viable Psychological construct? Is hypnosis an effective treatment for pain  relief? An evaluation of the effectiveness of subliminal advertising on buying habits